It is the first time since 1989-90 that Manchester United have lost 10 of their first 22 games of the league season.
Norwich City winger Borja Sainz has been suspended for six matches and fined 12,000 pounds ($14,749) for spitting at an opponent.
Graham Potter is in talks to replace Lopetegui, according to British media reports, and the former Chelsea and Brighton & Hove Albion manager is expected to take charge of West Ham for their FA Cup third-round game at Aston Villa on Friday.
IMAGES from the Premier League matches played on Saturday.
City slumped to a fourth consecutive loss in all competitions with a 2-1 defeat at Brighton & Hove Albion in the Premier League on Saturday
Qatar's Akram Afif has been named the Asian Football Confederation's Player of the Year for a second time with Kiko Seike from Japan securing the women's title at the regional body's annual awards ceremony in Seoul on Tuesday.
To mark World Mental Health Day, English footballer Connolly opens up about alcoholism, rehab
Brighton & Hove Albion and Nottingham Forest maintained unbeaten starts to the Premier League season with a topsy-turvy 2-2 draw as the visitors finished with 10 men and both managers were shown red cards in a feisty clash on Sunday.
Arsenal's Arteta wary of old foe Villa
Argentina host Chile at the Monumental stadium in Buenos Aires on September 5 before facing Colombia five days later in Barranquilla.
Reigning champions City are also involved in a separate independent hearing into the club's alleged breaches of Premier League financial regulations which began in September, with a verdict expected some time before the end of the current season.
Images from Thursday's action in the Premier League.
IMAGES from the EPL matches played on Saturday.
Arsenal moved up to second in the Premier League and within six points of Liverpool after a largely trouble-free, if slightly pedestrian, 1-0 win at home to struggling Ipswich Town on a chilly night in north London on Friday.
Three late goals from Amad Diallo dragged a below-par Manchester United to an unlikely 3-1 comeback victory over bottom side Southampton.
Liverpool hammered Sparta Prague 6-1 on Thursday to storm into the Europa League quarter-finals 11-2 on aggregate.
Liverpool draw Sparta Prague in Europa League last 16
Luton Town knocked out Everton and sixth tier Maidstone United upset Championship Ipswich Town
City open the season on Aug. 11, with the final round of matches scheduled for May 19, 2024.
A summary of Saturday's action in the English Premier League.
Brighton midfielder James Milner, who made his Premier League debut in 2002 at age 16, passed Ryan Giggs into second in all-time league appearances on Monday with 633 matches. He needs 20 more to equal Gareth Barry's record.
Tracking the key moves this week in the European transfer market
Liverpool strolled to a 2-0 victory over Brentford, while Newcastle drew 1-1 at Bournemouth.
Round-up of matches from the opening weekend of the English Premier League 2024-25
Phil Foden struck twice as Manchester City stepped up their bid for a fourth Premier League crown in a row with a ruthless 4-0 victory at Brighton & Hove Albion on Thursday.
Brighton secured their second victory of the competition with a comfortable win at Ajax thanks to goals from Ansu Fati and Simon Adingra.
The favourites to replace Erik ten Hag, who was sacked as Manchester United manager on Monday.
Liverpool will take on LASK, Union Saint-Gilloise and Toulouse in the Europa League group stage while debutants Brighton & Hove Albion will face Ajax Amsterdam and Olympique de Marseille following the draw on Friday.
Brazil missed a string of chances and were left to rue a lack of quality in the final third after they were held 0-0 by Costa Rica.
A round-up of Saturday's action in the English Premier League.
Arsenal closed the gap on leaders Liverpool with a 2-1 Premier League victory at Nottingham Forest
Vitaliy Mykolenko's 39th-minute own goal had put Luton ahead before Jack Harrison cheered the Everton faithful with an equaliser in the 55th minute, hammering in a low shot that Luton keeper Tim Krul allowed to let slip through his hands.
IMAGES from the Premier League match played between Brighton & Hove Albion and Manchester United on Thursday.
In Conte's absence, Stellini guided Spurs to wins over Manchester City, West Ham United and Chelsea.
The Englishman lasted 31 games, winning only 12, before the owners pulled the trigger.
Chelsea manager Graham Potter and his family have received anonymous death threats following the English Premier League club's poor run of results.
Liverpool lost 2-1 at Brighton & Hove Albion in the fourth round on Sunday
Manchester City roared back to the top of the Premier League with a 6-1 thrashing of Bournemouth after Manchester United steadied the ship
Jose Mourinho's side top Group G with a maximum nine points, three clear of second-placed Slavia.
Erik ten Hag's side, featuring several players who played in the World Cup in Qatar, could have doubled their lead when Anthony Martial's shot was well saved by Burnley goalkeeper Bailey Peacock-Farrell.
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